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Center for Clinical and Translational Science

CReSt Services

  • For Investigators

    • Study Startup & Clinical Operations Management - Coordinated guidance from concept to activation, ensuring a smooth launch.
    • Budgeting - Accurate, strategy-driven budgets aligned with institutional and sponsor expectations.
    • Research Coordination - Experienced clinical research coordinators provide day-to-day support for protocol implementation, including participant scheduling, data collection, regulatory documentation, and communication with sponsors and study teams.
    • Regulatory Support - Expert navigation through IRB submissions, compliance requirements, and documentation.
    • Feasibility - Clear, data-informed evaluations to determine protocol fit, resource availability, and enrollment potential.

    Scope of Services


    Phase I, Ila StudiesPhase llb-lVAncillary Services
    • First Time in Human Safety/Tolerance
    • Pharmacokinetics (PK)
    • Pharmacodynamics (PD)
    • PK/PD Correlations
    • Pharmacogenetics
    • Clinical Safety and Efficacy
    • Dose Ranging and Dose Definition
    • Labeling and Claims Support
    • Post Marketing Surveillance
    • Protocol Preparation
    • Study Design
    • Source Document Form Design
    • Database design
    • IRB Preparation and Submission
    • Budget Analysis and Negotiation
    • Study Coordinator Effort
    • Category B Devices

  • For Sponsors & CROs

    Systems currently utilized at our institution include:

    • IRAP – electronic research administration system (New system coming soon 2026)
    • Cerner – EMR system (EPIC coming soon February 2027)
    • i2b2 – de-identified repository of health information, used for finding patients meeting certain criteria
    • OnCore – clinical trials management system
    • REDCap – scheduling & data entry
    • Florence – eRegulatory binder service

    Our team has access to multiple facilities and equipment that offer clinical research support:

    • CH20 (Community Health Services Building 20): Administrative hub supporting public health initiatives and research coordination efforts.
    • UAB Hospital: Supports inpatient clinical trials with full integration into UAB’s academic medical infrastructure and billing systems.
    • The Kirklin Clinic (TKC): Major outpatient center enabling research in routine clinical workflows across 30+ specialties.
    • UAB Hospital–Highlands: Acute-care facility supporting research through coordinated services and integrated hospital systems.

    Community health care partners