J252202
Mentor: Dr. Brent Carter, Division of Pulmonary, Allergy and Critical Care Medicine
Description:
Dr. Brent Carter's lab does fundamental research in idiopathic pulmonary fibrosis (IPF) and asbestosis. They focus primarily on the role of macrophages (monocyte-derived macrophages) in driving fibrosis development and progression. Targeting these cells can attenuate or reverse fibrosis even after fibrosis is established. They also investigate the signaling between macrophages and fibroblasts, the cells that produce the scar. They use human cells that they obtain by bronchoalveolar lavage to validate what they do in mice and cell culture occurs in humans; transgenic mice that have a conditional deletion or overexpression in monocyte-derived macrophages or fibroblasts; and genetic manipulation in cell culture to over express or silence genes of interest.
Qualifications:
PhD, experience managing a project, work with mice, ability to do cell and molecular biology, flow cytometry, scRNA-seq, and works well with other scientists in the lab. Also need to keep good records of experiments, present at international meetings, and write well-constructed manuscripts.
To Apply:
Those interested should email Dr. Brent Carter at
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